Research by Dr. Wu and Colleagues Induces Fat Cells to Become iPS Cells

In a recently published paper, "Feeder-Free Derivation of Induced Pluripotent Stem Cells from Adult Human Adipose Stem Cells," senior author Joseph Wu, MD, PhD, assistant professor of medicine (cardiology) and radiology, and his colleagues describe how they reprogrammed fat cells (collected from adults undergoing liposuction) to become pluripotent stem (iPS) cells for use in tissue regeneration and disease research. According to Dr. Wu, "Fibroblasts, or skin cells, must be grown in the lab for three weeks or more before they can be reprogrammed. But these stem cells from fat are ready to go right away"(from "'Liposuction Leftovers' Easily Converted to iPS Cells, Study Shows" by Krista Conger http://med.stanford.edu/ism/2009/september/fat-cells.html or Download file.

Please click here to access the full research article "Feeder-Free Derivation of Induced Pluripotent Stem Cells from Adult Human Adipose Stem Cells," (published in Proceedings of the National Academy of Sciences (PNAS) 2009;106(37):15720-15725 http://www.pnas.org/content/106/37/15720.full.pdf) by Dr. Wu and his colleagues, which include co-author Michael Longaker, MD, professor of surgery (plastic/recon surgery) and (by courtesy) of bioengineering and first author Ning Sun, PhD, postdoctoral scholar in the Cardiovascular Gene and Cell Therapy Lab.

Comments

Post a comment