Radiology

News

Department of Radiology

September 2010

Announcements II: September 16, 2010

Medical Device Innovation: On September 27th at 5 PM in McCaw Hall at the Arrillaga Alumni Center, Jeffrey Shuren, MD, JD, director of the Food and Drug Administration (FDA)'s Center for Devices and Radiological Health, will be speaking about how the federal government can help private industry foster the development of lifesaving medical devices. Dr. Shuren will be discussing this issue with the following panelists: John Capek, PhD, executive vice president of medical devices at Abbott; Ross Jaffe, MD, managing director of Versant Ventures; Josh Makower, founder and CEO of Exploramed; and Stefanos Zenios, PhD, professor at Stanford’s Graduate School of Business.

To read more, please access "Media Advisory: Top FDA Official to Discuss Medical Device Innovation with Industry Leaders at Stanford."

New Faculty Hires and Promotions: Joe Wu, MD, PhD

Wu_100100.jpgJoseph Wu, MD, PhD, has been promoted to associate professor of medicine (cardiology) as well as radiology effective September 1. Prior to joining our faculty, Dr. Wu completed his fellowship and residency at the University of Los Angeles (UCLA) Medical Center. He received his MD from Yale University School of Medicine and his PhD from UCLA Department of Molecular Pharmacology.

Dr. Wu's clinical interests include adult congenital heart disease, nuclear cardiology, and echocardiography. His basic research focus is on the biological mechanisms of adult stem cells, embryonic stem cells, and induced pluripotent stem cells. He and his team use a combination of gene profiling, tissue engineering, physiological testing, and molecular imaging technologies to better understand stem cell biology in vitro and in vivo. They are interested in monitoring stem cell survival, proliferation, and differentiation for adult stem cells, while for embryonic stem cells, they are currently studying their tumorigenicity, immunogenicity, and differentiation. Further information is available at his lab website: http://wulab.stanford.edu/.

Dr. Wu has published over 100 articles. He has also received many awards, including the Burroughs Wellcome Fund Career Award for Biomedical Scientists, the American College of Cardiology Cardiovascular Imaging Award, the Baxter Foundation Faculty Award, the NIH Director’s New Innovator Award, and the NIH Transformative R01 Award.

To read more about Dr. Wu's prior awards, please see "In the News: Joe Wu, MD, PhD"; "Awards and Honors I: October 9, 2009"; "Research by Dr. Wu and Colleagues Induces Fat Cells to Become iPS Cells"; "Awards and Honors: April 17, 2009"; http://radiology.stanford.edu/blog/archives/2008/11/awards_and_hono_63.html; http://radiology.stanford.edu/blog/archives/2008/10/_joseph_wu_md_p.html ; http://radiology.stanford.edu/blog/archives/2008/06/awards_and_hono_42.html ; and http://radiology.stanford.edu/blog/archives/2007/04/awards_and_hono_1.html.

New Faculty Hires and Promotions: Michael Zeineh, MD, PhD

Zeineh_2010.gifMichael Zeineh, MD, PhD, joined the Department of Radiology as an assistant professor in the Neuroradiology Section on September 1, 2010. As an undergraduate at the California Institute of Technology, Dr. Zeineh developed an interest in advanced microscopic neuroscientific imaging, which led him to complete a combined MD-PhD program at the University of California, Los Angeles (UCLA). His PhD work focused on using high-resolution structural and functional MRI to investigate the neural underpinnings of memory formation and retrieval. Toward the end of his radiology residency at Stanford, he received a two-year Radiological Society of North America (RSNA) Research Fellowship to pursue high-field imaging in neuroradiology.

As a Stanford neuroradiology fellow, Dr. Zeineh was also awarded General Electric (GE) seed funding to support his ongoing research during his fellowship. His research work and interests are driven by the challenge to noninvasively characterize the microscopic pathology underlying neurologic disease, particularly disease entities with a significant component of pathology invisible to conventional imaging methods. Specifically, Dr. Zeineh utilizes high-field MRI, advanced susceptibility based processing, and diffusion tensor imaging, as well as other novel contrast mechanisms, with the following applications: 1) MR imaging and characterization of amyloid plaques in the brains of Alzheimer’s patients; 2) early in vivo biomarker imaging for Alzheimer’s disease; 3) improved imaging of seizure foci in localization-related epilepsy; 4) identifying network derangements and microstructural alterations in Parkinson’s disease; 5) imaging biomarkers for multiple sclerosis with quantitative imaging (measurement of myelin content); and 6) general applications of ultra-high field MRI for neurologic disease.

Announcements I: September 16, 2010

Free Flu Shots: Stanford will be offering free flu shots for faculty, staff, students, and retirees beginning Oct. 6th. For a flu clinic schedule, please access http://flu.stanford.edu/.

New Faculty Hires and Promotions: Roland Bammer, PhD

rbammer_2010_100.jpgRoland Bammer, PhD, has been promoted to associate professor of radiology (research) and, by courtesy, of neurology & neurological sciences effective August 1, 2010. Prior to joining our faculty in 2004 as an assistant professor, Dr. Bammer was a research associate at the Richard M. Lucas Center for Imaging. He earned his PhD in electrical engineering from Graz University of Technology, Graz, Austria. In 2002, he received his venia docendi (teaching professorship) in medical physics as well as biophysics from the Medical University of Graz, Austria.

His research interests include the development of novel imaging and reconstruction techniques that promise to significantly improve MR exams in both children and adult patients by reducing the overall scan time; improving the diagnostic capacity of the images; and providing an alternative contrast mechanism and the means to understand more clearly the underlying tissue microstructure, particularly in terms of how it is composed and how the brain is anatomically/functionally connected with different regions.

Dr. Bammer has published over 120 peer-reviewed articles, and he has 10 patents, with 4 pending. He has also earned many grants in support of his research and is currently principal investigator on one R21 and four R01 active research projects. In addition to these funding awards, he has received the following honors this past year: the Caffey Scientific Paper Award, 2010, from the Society for Pediatric Radiology and the Senior Fellow of the Freiburg Institute of Advanced Studies (FRIAS), 2010, from the University of Freiburg, Germany.

To view his other blog postings, please access "Awards and Honors: May 19, 2010"; "Awards and Honors: May 21, 2009"; and "Awards and Honors: September 14, 2007";

Announcements: September 13, 2010

Stanford Staffers Social Mixer: Thursday, September 16th, from 5:30 to 7:00 PM at Bangkok Bay Restaurant, Redwood City.

Date: Thursday, September 16
Time: 5:30 - 7:00

Place: Bangkok Bay Restaurant
825 El Camino, Redwood City

RSVP: Elizabeth Lasensky: lasensky@stanford.edu
by September 14

New Faculty Hires and Promotions: Andrei Iagaru, MD

Iagaru_09_100.pngDr. Iagaru recently joined our Department as an assistant professor of radiology, with a subspecialty in nuclear medicine. He completed medical school at Carol Davila University of Medicine, Bucharest, Romania, and an internship at Drexel University College of Medicine, Graduate Hospital, in the Department of Medicine. He began his residency at the University of Southern California (USC) Keck School of Medicine, Los Angeles, in the Division of Nuclear Medicine, where he was the chief resident. Dr. Iagaru finished his residency and completed a PET/CT fellowship at Stanford University's School of Medicine in the Division of Nuclear Medicine. His research interests include whole-body MRI and PET/CT for early cancer detection; clinical translation of novel PET radiopharmaceuticals; radioimmunotherapy; optical imaging of breast cancer; as well as PET/CT imaging for thyroid, breast, cervical and ovarian cancers, melanoma, lymphoma, and sarcomas.

Over the past three years as an instructor in Nuclear Medicine, Dr. Iagaru has received several awards including the Society of Nuclear Medicine (SNM) 2009 Image of the Year Award; SNM/American College of Nuclear Medicine (ACNM) Mid-Winter Conference 2010 Best Essay Award; 2009 Western Regional SNM Scientist Award; and a Stanford Cancer Center 2009 Developmental Cancer Research Award in Translational Science. With his interests, background, and training, Dr. Iagaru will find many opportunities for collaboration, teaching, and introducing his successful research into the clinical practice of nuclear medicine.

Please see his other award postings: "Awards and Honors: June 29, 2010"; "Awards and Honors: March 15, 2010"; "Awards and Honors: July 17, 2009"; "Awards and Honors: May 26, 2009"; and "Awards and Honors I: July 15, 2008".

New Faculty Hires and Promotions: Heike Daldrup-Link, MD

DaldrupLink_100.jpgHeike Daldrup-Link, MD, who was previously an associate professor of radiology and pediatrics at the University of California, San Francisco, (UCSF), joined the Stanford Department of Radiology September 1, 1010. She earned her medical degree from the University of Munster, Germany, in 1992 and completed a radiology residency and fellowship in pediatric radiology and molecular imaging at the Technical University of Munich, Germany, in 2004. While at UCSF as a research fellow, Dr. Daldrup-Link studied uses of contrast media for image enhancement. She currently leads several projects including “Monitoring of Stem Cell Engraftment in Arthritic Joints with MR Imaging” (R01); and “Novel Imaging Approach to Monitor Chondrogenic Differentiation of IPS Cells” (R21). Dr. Daldrup-Link is also a practicing radiologist with an interest in pediatric oncology, molecular imaging, general pediatric radiology, and teaching. She is member of the board of directors of the Society for Pediatric Radiology (SPR); member of the Children’s Oncology Group (COG); member of the editorial board of Pediatric Radiology; permanent member of the NIH Cancer Immunology and Immunotherapy Study Section; as well as a member of the program committees for the Association of University Radiologists (AUR) and Radiological Society of North America (RSNA) annual meetings. Recently, she published a textbook entitled Essentials of Pediatric Radiology: A Multimodality Approach, which provides a concise overview of both basic and complex topics encountered by pediatric radiologists in their daily practice. Her textbook also includes a free web-based case review and an online practice exam.

Stanford Radiology Kicks Off the Season

Paulson_200.jpgBy Nichole Paulson, OSC Lead Technologist at Stanford Medicine Outpatient Center

When the Stanford Football team plays, the musculoskeletal radiologist and imaging technologist of Stanford Radiology are not far away. They keep our team playing on the field by quickly diagnosing injuries. Our recently remodeled X-ray room at Stanford Stadium ensures that all of our patients, including the Stanford Football team, receive the best care available.

With the help of Radiology Business Analyst Tori Shannon, we have upgraded our equipment so that we have the latest in cutting-edge imaging technology that allows us to diagnose fractures and other injuries more accurately and faster than ever before. In the past, we used a portable machine and X-ray film that had to be hand carried and processed in the player locker room. However, our new Fuji portable machine is a digital X-ray unit with a built in processor that can display X-rays from injured football players within a couple of minutes. With our new upgrades, our imaging team can now take standing and weight-bearing X-rays, allowing for greater accuracy. Our new equipment also enables our imaging team to print and burn CD copies of the players' films, which not only benefits Stanford football players by reducing X-ray exposures from repeat films, but also members of visiting teams.

New Faculty Hires and Promotions: Jafi Lipson, MD

Jafi.gifDr. Jafi Lipson joined the Department of Radiology on August 1, 2010 as an assistant professor in the Breast Imaging Section. A graduate of Harvard College, UCSF School of Medicine, and UCSF Radiology Residency, Dr. Lipson completed her medical training as a Stanford Breast Imaging Fellow in June 2010. Her research interests include medical informatics applications in breast imaging and breast radiologic-pathologic correlation.

Her prior research activities focused on radiation dose with CT and the associated risk of cancer. As an NIH-funded T32 Research Fellow under the mentorship of Dr. Rebecca Smith-Bindman, Dr. Lipson conducted a study of four Bay Area hospitals in which she reviewed 1,200 CT examinations and dose reports; estimated the effective dose from each examination; and calculated the associated risk of cancer attributable to that effective dose. Her study culminated in an article entitled "Radiation Dose Associated with Common Computed Tomography Examinations and the Associated Lifetime Attributable Risk of Cancer" (Arch Intern Med. 2009 Dec 14;169(22):2078-86), which is one of only a few articles that have raised national attention regarding the issue of medical radiation and the need for clinical practice guidelines to track and reduce dose.

Dr. Lipson's current projects include the creation and evaluation of an Annotated Breast Map, which is an automated, WIKI-form visual summarization of a patient’s breast history; integration of the BI-RADS lexicon for mammography, ultrasound, and MRI into the RSNA RadLex lexicon; and classification and quantification of dynamic contrast enhanced breast MRI patterns of response to poly (ADP-ribose) polymerase (PARP) inhibitor therapy in the neoadjuvant treatment of triple-negative and BRCA-associated breast cancer.

Awards and Honors: September 3, 2010

Contag_100.jpgChristopher Contag, PhD, associate professor of pediatrics (neonatology); associate professor of microbiology & immunology; and associate professor (by courtesy) of radiology, has been awarded a grant by the California Institute for Regenerative Medicine (CIRM) to fund his stem cell research; he is one of four Stanford researchers to receive an award from the CIRM. According to a recent CIRM press release, "CIRM Allocates $25 Million to Overcome Immune Rejection of Stem Cell Transplantation Therapies," funded research will "develop strategies for overcoming rejection, eliminating potential barriers to moving stem cell therapies to the clinic."

Dr. Contag received both his BS (biology) and PhD (microbiology) from the University of Minnesota. He began his career at Stanford as a postdoctoral fellow in the Department of Microbiology and Immunology studying mother to infant transmission of HIV. This field of study brought him to the Department of Pediatrics, first as a pediatrics fellow in Division of Neonatal and Developmental Medicine, and then as an assistant professor in the Department of Pediatrics, specializing in neonatal and developmental medicine. In this position he sought to pull together the fields of microbiology, pediatrics, and radiology in projects aimed at imaging diseases of the neonate.

Currently, Dr. Contag serves as the associate chief (research) of the . . .

Division of Neonatal and Developmental Medicine and the director of both the Stanford Center for Innovation in In Vivo Imaging (SCI3) as well as the Stanford Center for Photomedicine. He is also the co-director of the Molecular Imaging Program at Stanford (MIPS). As director of the Molecular Biophotonics and Imaging Laboratory (MBIL), Dr. Contag, along with his colleagues, has used imaging to reveal the kinetics of stem cell engraftment and hematopoietic reconstitution, elucidating the nature of minimal residual disease states following cancer therapy and identifying tissue sites that pathogens use to evade the host immune response. Much of this work has used optical methods of molecular imaging, which are extremely powerful in preclinical models and have tremendous potential, but the Contag laboratory seeks to use a wide range of molecular imaging tools to study biology in living animals and humans.

Dr. Contag and his colleagues both develop and use these tools to address biological questions in a multimodality format. The focus of their efforts is the cells and molecules that control the body’s response to insult and that enable the regeneration of damaged tissues and organs. This has led to the development of miniaturized microscopes that can be used for early cancer detection, in vivo studies of cell biology, and image-guided resection.

As part of the recently awarded CIRM grant, Dr. Contag will work with his colleagues, Dr. Michael Bachmann, research associate in the Contag Lab, and Dr. Minnie Sarwall, professor of pediatrics (nephrology), on immunomodulators that can control graft rejection. These will be screened using an in vivo gene screen, where effector proteins are functionally selected in transplanted stem cells. This will reveal key molecules that control immune recognition and rejection, and will lead to selection of molecular targets for controlling rejection of stem cells and newly regenerated tissues.

Dr. Contag has authored over 200 publications; his other recent awards include the Achievement Award from the Society of Molecular Imaging, the opening plenary lecture at the European Society for Molecular Imaging in Warsaw, Poland, and an invited lecture at the Regenerative Medicine Conference in Hilton Head, South Carolina.

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